The Islamic State of Iraq and Syria or ISIS is on a massive land grab in the Middle East. Along the way they are stealing millions, brutalizing civilians, and slaughtering anyone who stands in their way. Much of the northern half of Iraq is in their control along with large parts of Syria. There are continued reports of ISIS fighters in the vicinity of the Golan Heights and incursions into Egypt's Sinai peninsula. What do these developments mean for Israel and are they prophetically significant? We will look at the realities on the ground and in the Bible to find answers to the question of Israel and the ISIS threat. Most of us know the basic facts about ISIS because the group has dominated recent headlines. We are well aware of their brutality, merciless slaughter of captives, and massive land grab in Iraq and Syria. We need to take a realistic look at the dangers posed to Israel and the prophetic implications of this enemy in the vicinity of the Jewish State.